{"id":4444,"date":"2024-02-08T09:39:02","date_gmt":"2024-02-08T09:39:02","guid":{"rendered":"http:\/\/rnce.inserm.fr\/non-classifiee\/escale-estelle\/"},"modified":"2024-05-29T09:16:55","modified_gmt":"2024-05-29T09:16:55","slug":"escale-estelle","status":"publish","type":"post","link":"https:\/\/rnce.inserm.fr\/en\/research-and-results\/escale-estelle\/","title":{"rendered":"ESCALE\/ESTELLE"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4444\" class=\"elementor elementor-4444 elementor-574\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-12633114 e-flex e-con-boxed e-con e-parent\" data-id=\"12633114\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-542aa8c9 elementor-widget elementor-widget-text-editor\" data-id=\"542aa8c9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>The objective of these two studies was:<strong><img fetchpriority=\"high\" decoding=\"async\" class=\"size-medium wp-image-2652 alignright\" src=\"https:\/\/rnce.inserm.fr\/wp-content\/uploads\/2024\/01\/Logo-ESCALE-ESTELLE-300x187.jpg\" alt=\"\" width=\"300\" height=\"187\" srcset=\"https:\/\/rnce.inserm.fr\/wp-content\/uploads\/2024\/01\/Logo-ESCALE-ESTELLE-300x187.jpg 300w, https:\/\/rnce.inserm.fr\/wp-content\/uploads\/2024\/01\/Logo-ESCALE-ESTELLE.jpg 367w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/strong><\/p><ul><li>to study the influence, on the risk of cancer in children, of the course of pregnancy, characteristics of the child at birth, the child&#8217;s environment in utero or during childhood, and their lifestyle.<\/li><li>to identify genetic predisposing factors.<\/li><li>to investigate potential interactions between genetic factors and environmental factors.<\/li><\/ul><p><strong>Methods<\/strong><\/p><ul><li>Cases were identified in pediatric oncology services; controls were recruited from telephone directories while respecting age, sex, and household size quotas.<\/li><li>The mothers of cases and controls were interviewed by telephone.<\/li><li>Blood or saliva samples were collected with informed consent.<br \/><br \/><\/li><\/ul><p>\n<table id=\"tablepress-1\" class=\"tablepress tablepress-id-1 tablepress-estelle\">\n<thead>\n<tr class=\"row-1 odd\">\n\t<th class=\"column-1\"><\/th><th class=\"column-2\">ESCALE 2003-2004<\/th><th class=\"column-3\"><\/th><th class=\"column-4\"><\/th><th class=\"column-5\">ESTELLE 2010-2011<\/th><th class=\"column-6\"><\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-hover\">\n<tr class=\"row-2 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">Interviews<\/td><td class=\"column-3\">ADN<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">Interviews<\/td><td class=\"column-6\">ADN<\/td>\n<\/tr>\n<tr class=\"row-3 odd\">\n\t<td class=\"column-1\">Leuc\u00e9mies<\/td><td class=\"column-2\">764<\/td><td class=\"column-3\">723<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">746<\/td><td class=\"column-6\">707<\/td>\n<\/tr>\n<tr class=\"row-4 even\">\n\t<td class=\"column-1\">Lymphomes<\/td><td class=\"column-2\">295<\/td><td class=\"column-3\">257<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">344<\/td><td class=\"column-6\">317<\/td>\n<\/tr>\n<tr class=\"row-5 odd\">\n\t<td class=\"column-1\">Tumeurs c\u00e9r\u00e9brales<\/td><td class=\"column-2\">209<\/td><td class=\"column-3\">176<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">302<\/td><td class=\"column-6\">254<\/td>\n<\/tr>\n<tr class=\"row-6 even\">\n\t<td class=\"column-1\">Neuroblastomes<\/td><td class=\"column-2\">191<\/td><td class=\"column-3\">154<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">200<\/td><td class=\"column-6\">166<\/td>\n<\/tr>\n<tr class=\"row-7 odd\">\n\t<td class=\"column-1\">N\u00e9phroblastomes<\/td><td class=\"column-2\">\u2013<\/td><td class=\"column-3\">\u2013<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">119<\/td><td class=\"column-6\">106<\/td>\n<\/tr>\n<tr class=\"row-8 even\">\n\t<td class=\"column-1\">H\u00e9patoblastomes<\/td><td class=\"column-2\">\u2013<\/td><td class=\"column-3\">\u2013<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">22<\/td><td class=\"column-6\">19<\/td>\n<\/tr>\n<tr class=\"row-9 odd\">\n\t<td class=\"column-1\">T\u00e9moins<\/td><td class=\"column-2\">1681<\/td><td class=\"column-3\">810<\/td><td class=\"column-4\"><\/td><td class=\"column-5\">1421<\/td><td class=\"column-6\">894<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-1 from cache --><\/p><p><strong>Regulatory aspects<\/strong><\/p><ul><li><strong>ESCALE<\/strong> CNIL n\u00b0902162 \u2013 RBM (DGS 2003\/0259)<\/li><li><strong>ESTELLE <\/strong> CNIL n\u00b0908283 \u2013 hors RBM -CPP Ile de France IV, 2008\/12NICB<\/li><\/ul><p>\u00a0<\/p><p><strong>Collaborations for genetic analyses:<\/strong> CNRGH\/CEA, Institut Pasteur Lille<\/p><p>\u00a0<\/p><p><strong>GWAS\/OMICS<\/strong><\/p><p>\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9a0bc4b elementor-widget elementor-widget-html\" data-id=\"9a0bc4b\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<script>\r\njQuery(document).ready(function($) {\r\nvar delay = 100; 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