5-year overall survival rates of childhood cancer in mainland France, by diagnostic groups and periods

Diagnostic groups and subgroups

2000-2004

2005-2009

2010-2016

p

I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases

83.0

[81.4-84.4]

87.0

[85.6-88.3]

87.6

[86.4-88.7]

**

I.a Lymphoid leukemias

89.2

[87.7-90.5]

91.0

[89.6-92.2]

89.9

[88.6-91.0]

I.b Acute myeloid leukemias

59.4

[54.3-64.1]

71.4

[66.2-76.0]

78.2

[74.2-81.7]

**

II. Lymphomas and reticuloendothelial neoplasms

93.6

[91.8-94.9]

93.2

[91.4-94.7]

95.8

[94.6-96.8]

*

II.a Hodgkin lymphomas

96.7

[94.5-98.0]

96.7

[94.4-98.1]

99.3

[98.2-99.7]

**

II.b Non-Hodgkin lymphomas (except Burkitt lymphomas)

91.2

[87.3-93.9]

86.6

[82.1-90.1]

90.5

[87.0-93.2]

II.c Burkitt lymphomas

91.4

[87.3-94.3]

95.2

[91.4-97.3]

95.4

[92.3-97.3]

III. CNS and miscellaneous intracranial and intraspinal neoplasms

71.1

[69.1-73.0]

74.7

[72.8-76.5]

76.5

[75.0-78.0]

**

III.a Ependymomas and choroid plexus tumors

62.5

[55.3-68.9]

77.6

[71.2-82.8]

80.8

[75.3-85.1]

**

III.b Astrocytomas

86.9

[84.4-89.1]

88.1

[85.5-90.2]

86.4

[84.3-88.2]

III.c Intracranial and intraspinal embryonal tumors

52.2

[47.3-56.9]

55.4

[50.4-60.1]

59.0

[54.6-63.1]

III.d Other gliomas

35.8

[30.2-41.5]

39.5

[34.0-44.9]

40.2

[35.4-45.0]

III.e Other specified intracranial and intraspinal neoplasms

93.8

[90.6-95.9]

95.8

[93.3-97.4]

95.7

[93.7-97.1]

IV. Neuroblastomas and other peripheral nervous cell tumors

72.7

[69.3-75.8]

75.3

[72.0-78.3]

80.3

[77.5-82.9]

**

IV.a Neuroblastomas and ganglioneuroblastomas

72.5

[69.1-75.7]

75.2

[71.8-78.2]

80.1

[77.2-82.7]

**

V. Retinoblastomas

99.2

[96.8-99.8]

98.5

[96.0-99.4]

100.0

-

VI. Renal tumors

91.6

[88.7-93.7]

92.9

[90.3-94.9]

93.3

[91.0-95.0]

VI.a Nephroblastomas and other nonepithelial renal tumors

92.0

[89.1-94.2]

92.9

[90.3-94.9]

93.7

[91.4-95.4]

VII. Hepatic tumors

83.1

[72.2-90.0]

78.3

[68.7-85.3]

87.0

[79.8-91.7]

VII.a Hepatoblastomas

86.9

[75.5-93.2]

82.0

[71.6-88.9]

87.1

[79.5-92.0]

VIII. Malignant bone tumors

74.6

[70.0-78.5]

75.2

[70.7-79.1]

73.1

[68.9-76.8]

VIII.a Osteosarcomas

73.1

[66.3-78.7]

74.1

[66.9-79.9]

68.0

[61.5-73.6]

VIII.c Ewing tumors and related bone sarcomas

74.7

[67.4-80.6]

74.1

[67.4-79.7]

77.0

[71.1-81.9]

IX. Soft tissue and other extraosseous sarcomas

69.0

[64.8-72.7]

73.5

[69.7-77.0]

74.8

[71.4-77.8]

IX.a Rhabdomyosarcomas

67.4

[61.6-72.4]

74.3

[69.0-78.8]

76.6

[71.9-80.5]

IX.b Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms

74.4

[57.6-85.3]

80.0

[64.0-89.5]

87.9

[76.1-94.0]

IX.d Other specified soft tissue sarcomas

72.1

[64.6-78.3]

71.3

[63.9-77.4]

69.6

[62.9-75.2]

IX.e Unspecified soft tissue sarcomas

60.0

[43.2-73.3]

70.7

[54.3-82.2]

70.3

[56.4-80.5]

X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads

92.3

[88.9-94.7]

93.1

[89.8-95.3]

96.5

[94.3-97.9]

X.a Intracranial and intraspinal germ cell tumors

91.8

[85.3-95.5]

94.0

[87.9-97.1]

96.5

[92.4-98.4]

X.b Malignant extracranial and extragonadal germ cell tumors

92.2

[84.4-96.2]

85.1

[76.2-90.9]

95.3

[89.1-98.0]

*

X.c Malignant gonadal germ cell tumors

95.7

[90.0-98.2]

98.3

[93.2-99.6]

99.2

[94.7-99.9]

XI. Other malignant epithelial neoplasms and malignant melanomas

92.8

[89-95.4]

93.3

[89.6-95.7]

93.3

[90.5-95.4]

XI.b Thyroid carcinomas

98.2

[93.0-99.5]

100.0

-

98.5

[93.9-99.6]

XI.d Malignant melanomas

84.1

[71.6-91.4]

87.2

[73.6-94.0]

90.2

[80.3-95.3]

XII. Other and unspecified malignant neoplasms

57.1

[28.4-78.0]

90.0

[65.6-97.4]

81.8

[63.9-91.4]

All cancers (excluding Langherhans cell histiocytosis)

80.8

[79.9-81.6]

83.3

[82.5-84.1]

84.6

[83.9-85.2]

**

Langherhans cell histiocytosis

94.3

[79.0-98.5]

97.1

[80.9-99.6]

89.1

[75.7-95.3]

All cancers (including Langherhans cell histiocytosis)

80.8

[80.0-81.7]

83.3

[82.5-84.1]

84.6

[83.9-85.3]

**

** pvalue <0.01; * pvalue < 0.05