BENCHISTA (Benchmarking International Survival by Toronto stage)
The overall survival rates for childhood cancer, based on population, vary across geographical regions in Europe and beyond; this variation could be explained at least in part by differences in tumor stage at the time of diagnosis. The international assessment of childhood cancer survival by stage, known as the BENCHISTA project, is a collaboration involving 70 population-based cancer registries from 25 European countries, Australia, Brazil, Japan, and Canada. The BENCHISTA project aims to apply the international consensus guidelines from Toronto on staging to six solid tumors in order to assess the extent of variation in stage at the time of diagnosis and to analyze how this contributes to differences in survival.
More than 10,000 cases of these six types of tumors diagnosed between 2014 and 2017 have been analyzed. This collaborative effort represents the first step towards understanding the reasons for the variation in overall survival for childhood cancer at the population level, by strengthening relationships between cancer registries, clinicians, representatives of the public/parents/patients, and other stakeholders to encourage research and improve outcomes.
The objective of this international study is to investigate the distribution of tumor stage at diagnosis for 6 pediatric solid cancers and to compare the stages at diagnosis and survival by stage for each tumor studied across the various participating countries.
Patients included: All patients enrolled in the RNCE during the period 2014-2016 with one of the following 6 types of cancer: medulloblastomas, neuroblastomas, nephroblastomas, osteosarcomas, bone Ewing tumors, rhabdomyosarcomas.
Data used : Data collected by the RNCE Gender, year of birth, year of cancer diagnosis, age at diagnosis, type of cancer, previous cancer and year, examinations performed for cancer staging, cancer stage, type of treatments received, potential relapse, vital status and time since diagnosis, cause of potential death.